Pharmacopoeial impurityCarvedilol EP Impurity ACat. No. P-C062-002CAS 1198090-73-1
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Active ingredient · Carvedilol family
Pharmaceutical analytical standardCarvedilol
Synonyms: 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol, Coreg, Dilatrend, Eucardic, Artist, Kredex, Dimitone, Querto, Korvasan, Coronis, Talliton, NSC 758694, Eucardic 25, Eucardic 12.5, Eucardic 6.25, Eucardic 3.125, Coropress, Dibloc, Pharmakon1600-01504257
- Cat. No.
- P-C062-001
- CAS
- 72956-09-3
- Alternative CAS
- 107741-96-8 (alternative CAS, same compound)
- Formula
- C24H26N2O4
- Molecular weight
- 406.48 g/mol
- Category
- Active ingredient (API)
A non-selective beta blocker that also blocks alpha-1 receptors, widening the blood vessels: patented in 1978 and approved in the United States in 1995, it is used for hypertension and heart failure. It also has antioxidant properties.
Did you know?Until the 1990s beta blockers were considered contraindicated in heart failure: in 1997 carvedilol became the first beta blocker approved in the United States for precisely this condition.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- CarvedilolBP 1168
- Carvedilol CRSEP Y0001427
- Carvedilol for system suitability CRSEP Y0001426
More products in the Carvedilol family
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Pharmacopoeial impurityCarvedilol EP Impurity CCat. No. P-C062-004CAS 72955-94-3
Pharmacopoeial impurityCarvedilol EP Impurity DCat. No. P-C062-005CAS 1391052-16-6
Pharmacopoeial impurityCarvedilol USP Related Compound DCat. No. P-C062-006CAS 51997-51-4
Pharmacopoeial impurityCarvedilol EP Impurity E HydrochlorideCat. No. P-C062-007CAS 64464-07-9
Pharmacopoeial impurityCarvedilol USP Related Compound ECat. No. P-C062-008CAS 1836-62-0
Pharmacopoeial impurityCarvedilol USP Related Compound FCat. No. P-C062-009CAS 1246820-73-4Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.