Active ingredientCefamandoleCat. No. P-C071-001CAS 34444-01-4
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Active ingredient · Cefamandole family
Pharmaceutical analytical standardCefamandole Nafate Sodium Salt
Synonyms: Cefamandole Nafate, Cephamandole nafate, Cefamandol nafato, Bergacef, Cedol, Mandolsan, Mandol, Cefam, NSC 299588, Kefadol, Mandokef, Cefaseptolo, Lampomandol, Neocefal, Pavecef, Kefandol
- Cat. No.
- P-C071-032
- CAS
- 42540-40-9
- Alternative CAS
- 57268-80-1 (free acid)
- Formula
- C19H17N6NaO6S2
- Molecular weight
- 512.49 g/mol
- Category
- Active ingredient (API)
Family: Cefamandole
A second-generation cephalosporin given by injection, introduced in 1977 in West Germany: it has been used for infections of the airways, skin, bones and urinary tract.
Did you know?It is given as cefamandole nafate, a formic acid ester that splits in the body to release the active drug; when the powder is dissolved for injection it gives off carbon dioxide.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Cefamandole nafate CRSEP C0682300
More products in the Cefamandole family
Active ingredientCefamandoleCat. No. P-C071-001CAS 34444-01-4
Active ingredientCefamandole Sodium SaltCat. No. P-C071-002CAS 30034-03-8
Pharmacopoeial impurityCefamandole EP Impurity ACat. No. P-C071-003CAS 1947364-12-6
Pharmacopoeial impurityCefamandole EP Impurity C Sodium SaltCat. No. P-C071-004CAS 36922-16-4
Pharmacopoeial impurityCefamandole EP Impurity ECat. No. P-C071-005CAS 87932-78-3
Isotopically labelledCefamandole Impurity 14-d5Cat. No. P-C071-006
Isotopically labelledCefamandole Impurity 16-d5Cat. No. P-C071-007
ImpurityCefamandole Dimer ImpurityCat. No. P-C071-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.