Active ingredient · Cinchophen family
Pharmaceutical analytical standardCinchophen
Synonyms: 2-phenylquinoline-4-carboxylic acid, Agotan, Atophan, Phenoquin, Quinophan, Quinophen, Cinconal, Quinofen, Tervalon, Mylofanol, Rhematan, Tophosan, Alutyl, Atocin, Rheumin, Tophol, Vantyl, Viophan, Artam, Aciphenochinoline, Aciphenochinolinium, Aminophan, Cincosal, Ikterosan, Phenophan, Traubofan, Artexin, Atigoa, Artamin, Acifenokinolin, Cincofene, Cincofeno, Cinchoninic acid, 2-phenyl-, Phenylcinchoninic Acid, NSC 2617, Aciphenochinolium, Aciphenocholinum, Methylium phenylcinchoninicum (for ester), Cinchopen, Atofan, Cincophen, Alutyo, Aciphenochinolinum, Aciphenochin, Rheumatan, Cincain, N-Cyclohexyl-2-phenyl-4-chinolincarboxamid, Cambridge id 5117240, NSC 70178, NSC 758887
- Cat. No.
- P-C168-001
- CAS
- 132-60-5
- Alternative CAS
- 59672-07-0 (lithium salt)
- 132-58-1 (hydrochloride)
- 114813-65-9 (sodium salt hydrate)
- 5949-18-8 (sodium salt)
- Formula
- C16H11NO2
- Molecular weight
- 249.27 g/mol
- Category
- Active ingredient (API)
An analgesic, chemically 2-phenylquinoline-4-carboxylic acid, synthesised in 1887 and launched in 1908 for gout because it reduced the build-up of uric acid; it has not been used in humans since the 1930s.
Did you know?Today it lives on in veterinary medicine: together with prednisolone it is the active ingredient of a preparation used for osteoarthritis in dogs.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
Shipped under controlled temperature when the molecule requires it.
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Sent with every order.
Follow your shipment live, from our warehouse to your lab.
More products in the Cinchophen family
Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
