Active ingredientNifedipineCat. No. P-N055-001CAS 21829-25-4
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Impurity or related compound · Nifedipine family
Pharmaceutical analytical standardcis-Nifedipine Pyrimidine Impurity
Synonyms: Nifedipine Impurity 14, Pyrimidine Impurity
- Cat. No.
- P-N055-043
- CAS
- 80742-11-6
- Alternative CAS
- N/A
- Formula
- C19H18N4O6
- Molecular weight
- 398.38 g/mol
- Category
- Impurity or related compound
Family: Nifedipine
A dihydropyridine calcium channel blocker that widens blood vessels, developed in Germany, patented in 1967 and approved in the United States in 1981; it is used for high blood pressure and angina.
Did you know?It is very sensitive to light: in daylight it readily turns into a nitrosophenylpyridine derivative, so in the laboratory it is analysed in the dark or under golden light.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Nifedipine family
Active ingredientNifedipineCat. No. P-N055-001CAS 21829-25-4
Pharmacopoeial impurityNifedipine EP Impurity ACat. No. P-N055-002CAS 67035-22-7
Pharmacopoeial impurityNifedipine EP Impurity C (Z-Isomer)Cat. No. P-N055-003CAS 111304-31-5
Pharmacopoeial impurityNifedipine EP Impurity C (as E/Z-Mixture)Cat. No. P-N055-004CAS 39562-27-1
Pharmacopoeial impurityNifedipine EP Impurity D (Z)Cat. No. P-N055-005CAS 14205-39-1
Pharmacopoeial impurityNifedipine EP Impurity D (E)Cat. No. P-N055-006CAS 80012-11-9
MetaboliteNifedipine MetaboliteCat. No. P-N055-007CAS 34783-31-8
MetaboliteNifedipine Metabolite lactoneCat. No. P-N055-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.