Impuritycis-Diammine-Diiodo Platinum IICat. No. P-C176-002CAS 13841-96-8
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Active ingredient · Cisplatin family
Pharmaceutical analytical standardCisplatin
Synonyms: Citoplatino, Cysplatyna, Metaplatin, Plastistil, Platiblastin, Platinoxan, Abiplatin, Blastolem, Cisplatyl, Citosin, Platiran, Platistin, Platosin, Placis, Platiblastin-S, DDPt, CisPt(II), CPDD, Dichlorodiammineplatinum, cis-platinum ii, Platinol-AQ VHA Plus, DDP (antitumor agent), Platidiam Lachema BRNO, Platinum diamminodichloride, Cis Diamminedichloroplatinum, Cis-diamminedichloridoplatinum, cis-Dichlorodiamminoplatinum(II), Cis-platinous Diamine Dichloride, Cis-dichloroammine Platinum (II), cis-Dichlorodiammine platinum(II), Platinum, Diaminedichloro-, cis-, Cis-diamminedichloro Platinum (II), Cis-platinum II Diamine Dichloride, Briplatin, CACP, CDDP, Cis Platinum, Cis-DDP, cis-diammineplatinum(II) dichloride, Cismaplat, Diamminodichloride, Platinum, Dichloroplatinumdiamine, Fauldiscipla, Lederplatin, Liplacis, Neoplatin, Platamine, Platidiam, Platinex, Platinol, Platinol-Aq, Platinum, diamminedichloro-, (SP-4-2)-, Diammine(dichloro)platinum
- Cat. No.
- P-C176-001
- CAS
- 15663-27-1
- Alternative CAS
- N/A
- Formula
- Cl2H6N2Pt
- Molecular weight
- 300.04 g/mol
- Category
- Active ingredient (API)
A platinum-based chemotherapy drug, first synthesised in the mid-19th century by Italian chemist Michele Peyrone: its anticancer activity was discovered in the 1960s and in the United States it was approved in 1978 for testicular and ovarian cancer.
Did you know?It was found by chance: Barnett Rosenberg passed current between platinum electrodes in a culture of Escherichia coli and the bacteria stopped dividing. The cause was not the current, but a platinum compound from the electrodes.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- CisplatinBP 809
- Cisplatin CRSEP C2210000
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Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.