Active ingredientCodeine MonohydrateCat. No. P-C237-001CAS 6059-47-8
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Pharmacopoeial impurity · Codeine family
Pharmaceutical analytical standardCodeine EP Impurity D
Synonyms: 3-O-(Codein-2-yl)morphine, Codeine Impurity D
- Cat. No.
- P-C237-005
- CAS
- 2585669-81-2
- Alternative CAS
- N/A
- Formula
- C35H38N2O6
- Molecular weight
- 582.70 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Codeine
A natural alkaloid found in the sap of the opium poppy, first isolated in 1832 in France by chemist Pierre Robiquet; it is used as an analgesic for mild to moderate pain and to relieve cough.
Did you know?Its name comes from the Greek kodeia, the poppy head; it makes up about 2% of opium, and in the liver the enzyme CYP2D6 converts a small part of it into morphine.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Codeine family
Active ingredientCodeine MonohydrateCat. No. P-C237-001CAS 6059-47-8
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Pharmacopoeial impurityCodeine EP Impurity E (alpha-Isomer)Cat. No. P-C237-006CAS 16589-96-1
Pharmacopoeial impurityCodeine EP Impurity ECat. No. P-C237-007CAS 1777-89-5
Pharmacopoeial impurityCodeine EP Impurity FCat. No. P-C237-008CAS 4829-46-3
Pharmacopoeial impurityCodeine EP Impurity HCat. No. P-C237-009CAS 467-15-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.