Active ingredientTrospium ChlorideCat. No. P-T230-001CAS 10405-02-4
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Impurity or related compound · Trospium family
Pharmaceutical analytical standardDehydro Trospium Chloride
Synonyms: Trospium Chloride Impurity 23
- Cat. No.
- P-T230-015
- CAS
- 113922-55-7
- Alternative CAS
- N/A
- Formula
- C25H28NO3·Cl
- Molecular weight
- 425.95 g/mol
- Category
- Impurity or related compound
Family: Trospium
A quaternary ammonium antimuscarinic, patented in 1966 and in medical use since 1974; in the United States it has been approved since 2004 for overactive bladder with urgency and incontinence.
Did you know?As a quaternary cation it barely crosses the blood-brain barrier and stays outside the brain: this is why it has been paired with xanomeline in a combination medicine, where it limits xanomeline's side effects in the rest of the body.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Trospium family
Active ingredientTrospium ChlorideCat. No. P-T230-001CAS 10405-02-4
Pharmacopoeial impurityTrospium EP Impurity BCat. No. P-T230-003CAS 16444-19-2
Pharmacopoeial impurityTrospium EP Impurity ACat. No. P-T230-004CAS 76-93-7
Pharmacopoeial impurityTrospium EP Impurity B HydrochlorideCat. No. P-T230-005CAS 63516-30-3
Pharmacopoeial impurityTrospium EP Impurity CCat. No. P-T230-006CAS 3464-71-9
MetaboliteTrospium O-beta-GlucuronideCat. No. P-T230-007
Isotopically labelledTrospium EP Impurity C-d8 ChlorideCat. No. P-T230-010
Isotopically labelledTrospium-d8 ChlorideCat. No. P-T230-011Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.