Active ingredientErgotamine TartrateCat. No. P-E083-001CAS 379-79-3
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Impurity or related compound · Ergotamine family
Pharmaceutical analytical standardDihydrolysergic Acid
Synonyms: Ergoline-8-carboxylic acid, 6-methyl-, (8beta)-, Lysergic acid, dihydro-, Ergoline-8beta-carboxylic acid, 6-methyl-
- Cat. No.
- P-E083-012
- CAS
- 5878-43-3
- Alternative CAS
- N/A
- Formula
- C16H18N2O2
- Molecular weight
- 270.33 g/mol
- Category
- Impurity or related compound
Family: Ergotamine
An alkaloid produced by ergot, the fungus Claviceps purpurea that parasitises cereals: isolated in 1918 by Swiss chemist Arthur Stoll and marketed from 1921, it is used to treat and prevent migraine attacks, often together with caffeine.
Did you know?Ergot was known to physicians long before the molecule: as early as the 16th century it was used to induce childbirth, and later to prevent bleeding after delivery.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Ergotamine family
Active ingredientErgotamine TartrateCat. No. P-E083-001CAS 379-79-3
Pharmacopoeial impurityDihydro Ergotamine Mesylate EP Impurity BCat. No. P-E083-002CAS 3609-19-6
Pharmacopoeial impurityDihydro Ergotamine Mesylate EP Impurity DCat. No. P-E083-003CAS 5550-75-4
Pharmacopoeial impurityDihydro Ergotamine Mesylate EP Impurity ECat. No. P-E083-004CAS 17479-19-5
Pharmacopoeial impurityErgotamine EP Impurity ACat. No. P-E083-006CAS 72170-28-6
Impurity8'-Hydroxy Dihydroergotamine (Mixture of Diastereomers)Cat. No. P-E083-007CAS 90650-44-5
ImpurityDihydro ErgosineCat. No. P-E083-008CAS 7288-61-1
ImpurityDihydro Ergotamine MesylateCat. No. P-E083-009CAS 6190-39-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.