Active ingredientDiosminCat. No. P-D137-001CAS 520-27-4
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Impurity or related compound · Diosmin family
Pharmaceutical analytical standardDiosmin Impurity 8
Synonyms: 2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-2,3-dihydrochromen-4-one
- Cat. No.
- P-D137-025
- CAS
- 67549-69-3
- Alternative CAS
- N/A
- Formula
- C21H24O8
- Molecular weight
- 404.42 g/mol
- Category
- Impurity or related compound
Family: Diosmin
A flavonoid found mainly in citrus peel and also obtained by converting hesperidin: since 1969 it has been used as a phlebotonic and vascular protector for venous insufficiency and haemorrhoids.
Did you know?When it was first isolated, in 1925, it did not come from citrus fruit but from a European herbaceous plant, the common figwort (Scrophularia nodosa).
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Diosmin family
Active ingredientDiosminCat. No. P-D137-001CAS 520-27-4
Pharmacopoeial impurityDiosmin EP Impurity ACat. No. P-D137-002CAS 6100-74-9
Pharmacopoeial impurityDiosmin EP Impurity BCat. No. P-D137-003CAS 520-26-3
Pharmacopoeial impurityDiosmin EP Impurity CCat. No. P-D137-004CAS 552-57-8
Pharmacopoeial impurityDiosmin EP Impurity DCat. No. P-D137-005CAS 1431536-92-3
Pharmacopoeial impurityDiosmin EP Impurity ECat. No. P-D137-006CAS 480-36-4
Pharmacopoeial impurityDiosmin EP Impurity FCat. No. P-D137-007CAS 520-34-3
Pharmacopoeial impurityDiosmin EP Impurity GCat. No. P-D137-008CAS 520-33-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.