Active ingredientDoxapramCat. No. P-D179-001CAS 309-29-5
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Pharmacopoeial impurity · Doxapram family
Pharmaceutical analytical standardDoxapram EP Impurity A
Synonyms: 4-(2-Chloroethyl)-1-ethyl-3,3-diphenylpyrrolidin-2-one, Doxapram impurity a
- Cat. No.
- P-D179-003
- CAS
- 3192-64-1
- Alternative CAS
- N/A
- Formula
- C20H22ClNO
- Molecular weight
- 327.85 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Doxapram
A respiratory stimulant (analeptic) acting on the chemoreceptors of the carotid bodies, studied as early as the 1960s: it is used in hospital, for short periods, in acute respiratory failure and drug-induced respiratory depression.
Did you know?It is not only used in humans: in aquariums and research centres it has also helped captive sharks and rays to recover after general anaesthesia.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Doxapram family
Active ingredientDoxapramCat. No. P-D179-001CAS 309-29-5
Active ingredientDoxapram Hydrochloride MonohydrateCat. No. P-D179-002CAS 7081-53-0
Pharmacopoeial impurityDoxapram EP Impurity BCat. No. P-D179-004CAS 1688-76-2
Isotopically labelledDoxapram-d5Cat. No. P-D179-005
Isotopically labelledMorpholine-13C4Cat. No. P-D179-007CAS 1217024-56-0
Impurity2-KetodoxapramCat. No. P-D179-008CAS 42595-88-0
ImpurityDoxapram N-OxideCat. No. P-D179-009CAS 2724726-82-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.