Active ingredientDroxidopaCat. No. P-D194-001CAS 23651-95-8
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Impurity or related compound · Droxidopa family
Pharmaceutical analytical standardDroxidopa Impurity 3
- Cat. No.
- P-D194-017
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C17H15NO6
- Molecular weight
- 329.31 g/mol
- Category
- Impurity or related compound
Family: Droxidopa
A synthetic amino acid that the body converts into noradrenaline. In use in Japan since 1989 and approved in the United States in 2014, it treats neurogenic orthostatic hypotension, the drop in blood pressure on standing seen in disorders of the autonomic nervous system such as multiple system atrophy.
Did you know?It is also known as L-DOPS. Unlike noradrenaline it can cross the blood-brain barrier, and it is converted by the same enzyme that turns levodopa into dopamine, DOPA decarboxylase.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Droxidopa family
Active ingredientDroxidopaCat. No. P-D194-001CAS 23651-95-8
Isotopically labelledDL-threo-Droxidopa-13C2-15N HClCat. No. P-D194-002CAS 1329556-63-9
Isotopically labelledDroxidopa Impurity 11 Hydrochloride-13C-d3Cat. No. P-D194-003
Isotopically labelledDroxidopa Impurity 11-13C2-15NCat. No. P-D194-004
Isotopically labelledDroxidopa Impurity 12-13C2-15NCat. No. P-D194-005
Isotopically labelledDroxidopa-13C6Cat. No. P-D194-006
Isotopically labelledL-threo-Droxidopa-13C2-15NCat. No. P-D194-007CAS 1276295-04-5
Isotopically labelledL-threo-Droxidopa-13C2-15N HClCat. No. P-D194-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.