Active ingredientEsmololCat. No. P-E095-001CAS 81147-92-4
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Active ingredient · Esmolol family
Pharmaceutical analytical standardEsmolol Hydrochloride
Synonyms: Brevibloc, Brevibloc in plastic container, Brevibloc Double Strength in plastic container, Benzenepropanoic acid, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, methyl ester, hydrochloride, CLOL
- Cat. No.
- P-E095-002
- CAS
- 81161-17-3
- Alternative CAS
- 81147-92-4 (free base)
- 103598-03-4 (free base)
- 81147-93-5 (sulfate)
- Formula
- C16H25NO4·HCl
- Molecular weight
- 331.84 g/mol
- Category
- Active ingredient (API)
Family: Esmolol
An ultra-short-acting cardioselective beta-blocker, patented in 1980 and in use since the late 1980s: it is given intravenously to control heart rate quickly, for example in the operating theatre and in supraventricular tachycardias.
Did you know?It is a 'soft drug' designed to be short-lived: enzymes in red blood cells cleave its ester bond and its half-life is about 9 minutes. The name recalls it too: es-molol stands for ester-methyl.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Esmolol family
Active ingredientEsmololCat. No. P-E095-001CAS 81147-92-4
MetaboliteEsmolol AcidCat. No. P-E095-003CAS 81148-15-4
Isotopically labelledEsmolol-d7 Acid Sodium SaltCat. No. P-E095-004
Isotopically labelledEsmolol-d7 HClCat. No. P-E095-005CAS 1346598-13-7
NitrosamineN-Nitroso EsmololCat. No. P-E095-006
NitrosamineN-Nitroso Esmolol AcidCat. No. P-E095-007
NitrosamineN-Nitroso Esmolol DimerCat. No. P-E095-008
NitrosamineN-Nitroso N-Ethyl EsmololCat. No. P-E095-009Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.