Active ingredientEstetrolCat. No. P-E099-001CAS 15183-37-6
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Stable isotope labelled · Estetrol family
Pharmaceutical analytical standardEstetrol-d3
- Cat. No.
- P-E099-006
- CAS
- N/A
- Alternative CAS
- 15183-37-6 (unlabelled form)
- Formula
- C18H21D3O4
- Molecular weight
- 307.40 g/mol
- Category
- Stable isotope labelled
Family: Estetrol
A natural oestrogen discovered in 1965 in Stockholm, made exclusively by the foetal liver during pregnancy; since 2021 it has been used with drospirenone in a contraceptive pill.
Did you know?Its nickname E4 refers to its four hydroxyl groups; the estetrol used in medicines does not come from foetal sources but is synthesised from plant sterols in soybeans.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Estetrol family
Active ingredientEstetrolCat. No. P-E099-001CAS 15183-37-6
Active ingredientEstetrol 17-AcetateCat. No. P-E099-002CAS 690996-23-7
Active ingredientEstetrol 3-Sulfate Sodium SaltCat. No. P-E099-003
Active ingredientEstetrol MonohydrateCat. No. P-E099-004CAS 2055649-81-3
MetaboliteEstetrol 3-GlucuronideCat. No. P-E099-005
Isotopically labelledEstetrol-d4 (Major)Cat. No. P-E099-007
ImpurityEstetrol Impurity 1Cat. No. P-E099-008CAS 58001-91-5
Impurity15,16-Dehydro Estradiol 3-Benzyl EtherCat. No. P-E099-009CAS 690996-26-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.