Active ingredientBenzocaineCat. No. P-B043-001CAS 94-09-7
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Impurity or related compound · Benzocaine family
Pharmaceutical analytical standardEthyl 4-Formamidobenzoate
Synonyms: N-Formylbenzocaine, Benzoic acid, 4-(formylamino)-, ethyl ester, Benzocaine N-Formyl Impurity, NSC 12009
- Cat. No.
- P-B043-024
- CAS
- 5422-63-9
- Alternative CAS
- N/A
- Formula
- C10H11NO3
- Molecular weight
- 193.20 g/mol
- Category
- Impurity or related compound
Family: Benzocaine
An ester-type local anaesthetic, synthesised in 1890 in Eberbach by German chemist Eduard Ritsert and on the market since 1902. Poorly soluble in water, it is used on the skin and mucous membranes: sore throats, mouth ulcers, toothache, sunburn.
Did you know?It is not only for humans: dissolved in a water bath, it is commonly used to anaesthetise amphibians, such as frogs and salamanders, before surgery.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Benzocaine family
Active ingredientBenzocaineCat. No. P-B043-001CAS 94-09-7
Pharmacopoeial impurityBenzocaine EP Impurity ACat. No. P-B043-002CAS 623-04-1
Pharmacopoeial impurityBenzocaine EP Impurity CCat. No. P-B043-003CAS 582-33-2
Pharmacopoeial impurityBenzocaine EP Impurity DCat. No. P-B043-005CAS 87-25-2
Pharmacopoeial impurityBenzocaine EP Impurity FCat. No. P-B043-006CAS 1877-77-6
Isotopically labelledBenzocaine-d4Cat. No. P-B043-007CAS 342611-08-9
NitrosamineEthyl 4-(methylnitrosoamino)benzoateCat. No. P-B043-008CAS 208176-48-1
Pharmacopoeial impurity4-Aminobenzoic AcidCat. No. P-B043-009CAS 150-13-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.