Isotopically labelledFenbufen-d9Cat. No. P-F018-002CAS 1189940-96-2
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Active ingredient · Fenbufen family
Pharmaceutical analytical standardFenbufen
Synonyms: 4-oxo-4-(4-phenylphenyl)butanoic acid, gamma-Oxo(1,1'-biphenyl)-4-butanoic acid, NSC 757812, Lederfen cp, Lederfen f, Fenbuzip 300, Fenbuzip 450, Lederfen 450, Lederfen, Cinopal, Bufemid, Napanol, Propionic acid, 3-(4-biphenylylcarbonyl)-, Cinopol, Beta,p-Phenylbenzoylpropionic acid, Diphenyl-4-gamma-oxo-gamma-butyric acid, Pharmakon1600-01501008
- Cat. No.
- P-F018-001
- CAS
- 36330-85-5
- Alternative CAS
- 77479-09-5 (sodium salt)
- Formula
- C16H14O3
- Molecular weight
- 254.28 g/mol
- Category
- Active ingredient (API)
A non-steroidal anti-inflammatory drug derived from arylbutyric acid, patented as a medicine in the early 1970s and used for osteoarthritis and inflammatory pain: it is a prodrug that the body converts into biphenylacetic acid (felbinac).
Did you know?The molecule had already been described in a 1936 patent and in chemistry papers from 1940, decades before its anti-inflammatory action was put to use.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- FenbufenBP 354
- Fenbufen CRSEP F0041000
More products in the Fenbufen family
Isotopically labelledFenbufen-d9Cat. No. P-F018-002CAS 1189940-96-2
ImpurityFenbufen Impurity 1Cat. No. P-F018-003CAS 6918-68-9
Impurity4-(4-Chlorophenyl)-4-oxobutanoic AcidCat. No. P-F018-004CAS 3984-34-7
ImpurityBiphenylCat. No. P-F018-005CAS 92-52-4
ImpurityFenbufen Ethyl EsterCat. No. P-F018-006CAS 1230-54-2
ImpurityFenbufen Isopropyl EsterCat. No. P-F018-007CAS 2725579-21-3
ImpurityFenbufen Methyl EsterCat. No. P-F018-008CAS 54011-27-7Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.