Active ingredientFoscarnet SodiumCat. No. P-F118-001CAS 63585-09-1
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Pharmacopoeial impurity · Foscarnet family
Pharmaceutical analytical standardFoscarnet Sodium EP Impurity C
Synonyms: Ethyl sodium (ethoxycarbonyl)phosphonate, sodium ethoxy(ethoxycarbonyl)phosphinate, Sodium ethyl ethoxycarbonylphosphonate, Ethyl ethoxy(hydroxy)phosphinecarboxylate oxide sodium salt, Foscarnet Sodium Hexahydrate EP Impurity C
- Cat. No.
- P-F118-005
- CAS
- 72304-94-0
- Alternative CAS
- N/A
- Formula
- C5H10NaO5P
- Molecular weight
- 204.09 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Foscarnet
An antiviral that mimics pyrophosphate and occupies its binding site on viral DNA polymerases; approved in 1991, it is used mainly for cytomegalovirus retinitis and for herpesviruses resistant to other drugs.
Did you know?Unlike aciclovir and ganciclovir it does not need to be activated by viral enzymes: it works as it is, which is why it is also effective against strains resistant to those drugs.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Foscarnet family
Active ingredientFoscarnet SodiumCat. No. P-F118-001CAS 63585-09-1
Active ingredientFoscarnet Sodium HexahydrateCat. No. P-F118-002CAS 34156-56-4
Pharmacopoeial impurityFoscarnet Sodium EP Impurity ACat. No. P-F118-003CAS 72305-00-1
Pharmacopoeial impurityFoscarnet Sodium EP Impurity B (as Disodium Salt)Cat. No. P-F118-004CAS 55920-24-6
Pharmacopoeial impurityFoscarnet Sodium EP Impurity DCat. No. P-F118-006CAS 1474-78-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.