Active ingredientFosfomycinCat. No. P-F121-001CAS 23155-02-4
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Active ingredient · Fosfomycin family
Pharmaceutical analytical standardFosfomycin Calcium Monohydrate
Synonyms: Fosfomycin calcium hydrate, Monocalcium (-)-(1R,2S)-(1,2-epoxypropyl)phosphonate mono hydrate
- Cat. No.
- P-F121-003
- CAS
- 26469-67-0
- Alternative CAS
- 23155-02-4 (free acid)
- 27354-29-6 (free acid)
- 33996-10-0 (sodium salt)
- 26016-98-8 (anhydrous form)
- 26472-47-9 (anhydrous form)
- 26016-99-9 (sodium salt)
- 25030-61-9 (sodium salt)
- 26136-10-7 (magnesium salt)
- 78964-85-9 (tromethamine)
- Formula
- C3H5CaO4P·H2O
- Molecular weight
- 194.14 g/mol
- Category
- Active ingredient (API)
Family: Fosfomycin
An antibiotic that blocks the enzyme MurA, the first step in building the bacterial cell wall. It was discovered in cultures of the soil bacterium Streptomyces fradiae by Spanish and American researchers, who published it in 1969; it is used, among other things, for cystitis.
Did you know?The producing strain came from a soil sample collected in 1966 along the road from Jávea to Gata de Gorgos, in the province of Alicante, and was isolated by Spanish microbiologist Sagrario Mochales.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Fosfomycin calcium CRSEP Y0000782
More products in the Fosfomycin family
Active ingredientFosfomycinCat. No. P-F121-001CAS 23155-02-4
Active ingredientFosfomycin CalciumCat. No. P-F121-002CAS 26016-98-8
Active ingredientFosfomycin Disodium SaltCat. No. P-F121-004CAS 26016-99-9
Active ingredientFosfomycin tromethamineCat. No. P-F121-005CAS 78964-85-9
Pharmacopoeial impurityFosfomycin EP Impurity A Ammonium SaltCat. No. P-F121-006CAS 1160525-87-0
Pharmacopoeial impurityFosfomycin Trometamol EP Impurity ACat. No. P-F121-009CAS 84954-80-3
Pharmacopoeial impurityFosfomycin Trometamol EP Impurity A Di-Ammonium SaltCat. No. P-F121-010
Pharmacopoeial impurityFosfomycin Trometamol EP Impurity A Disodium SaltCat. No. P-F121-011Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.