Active ingredientGadodiamideCat. No. P-G004-001CAS 131410-48-5
Drag to rotate
Pharmacopoeial impurity · Gadodiamide family
Pharmaceutical analytical standardGadodiamide EP Impurity B
Synonyms: Gadolinium Sodium Diethylenetriamine Pentaacetic Acid, Dipentast, Gadolinium disodium diethylenetriamine pentaacetic acid
- Cat. No.
- P-G004-003
- CAS
- 92923-64-3
- Alternative CAS
- 67-43-6 (free form)
- 1004765-76-7 (free form)
- 7578-43-0 (sodium salt)
- 1420-46-8 (sodium salt)
- 12111-24-9 (calcium salt sodium salt)
- 62796-80-9 (calcium salt sodium salt)
- 207226-35-5 (calcium salt sodium salt hydrate)
- Formula
- C14H18GdN3Na2O10
- Molecular weight
- 591.54 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Gadodiamide
A gadolinium-based contrast agent for magnetic resonance imaging, approved in 1993: injected into a vein, it helps visualise blood vessels and lesions in the brain, spine and rest of the body. In 2017 the European Medicines Agency suspended its use.
Did you know?The gadolinium that makes it visible on MRI is named after the mineral gadolinite, which in turn honours the chemist Johan Gadolin, who first analysed it in 1794.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Gadodiamide impurity B CRSEP Y0001877
More products in the Gadodiamide family
Active ingredientGadodiamideCat. No. P-G004-001CAS 131410-48-5
Pharmacopoeial impurityGadodiamide EP Impurity A Sodium SaltCat. No. P-G004-002Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.