Active ingredientTretinoinCat. No. P-T187-001CAS 302-79-4
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Impurity or related compound · Tretinoin family
Pharmaceutical analytical standardgamma-Ionone
Synonyms: Retinoic Acid Related Compound 14, Ionone, gamma-, g-Ionone, FEMA No. 3175, g-Ionon, Isotretinoin Impurity 12
- Cat. No.
- P-T187-045
- CAS
- 49816-69-5
- Alternative CAS
- 79-76-5 (alternative CAS, same compound)
- Formula
- C13H20O
- Molecular weight
- 192.30 g/mol
- Category
- Impurity or related compound
Family: Tretinoin
It is all-trans retinoic acid, the acid form of vitamin A that guides cell growth and maturation: it is applied to the skin for acne and, taken by mouth, treats acute promyelocytic leukaemia.
Did you know?In 1985 in Shanghai, Wang Zhenyi's group used it to treat a 5-year-old girl with promyelocytic leukaemia: instead of killing the diseased cells, it pushes them to mature into normal white blood cells.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Tretinoin family
Active ingredientTretinoinCat. No. P-T187-001CAS 302-79-4
Pharmacopoeial impurityTretinoin EP Impurity BCat. No. P-T187-006CAS 5352-74-9
Pharmacopoeial impurityTretinoin EP Impurity CCat. No. P-T187-007CAS 3555-80-4
Pharmacopoeial impurityTretinoin EP Impurity DCat. No. P-T187-008CAS 5300-03-8
Pharmacopoeial impurityTretinoin EP Impurity FCat. No. P-T187-009CAS 81121-20-2
Metabolite9-cis-Retinoic Acid GlucuronideCat. No. P-T187-010
MetaboliteTretinoin GlucuronideCat. No. P-T187-011CAS 401-10-5
Isotopically labelled4-Keto-9-cis Retinoic acid-d3Cat. No. P-T187-012CAS 1185241-31-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.