Active ingredient · Gonadorelin family
Pharmaceutical analytical standardGonadorelin for NMR identification
Synonyms: Gonadorelinum, Gonadorelin, Gonadorelina, GnRH-I, Fertagyl, LH-Releasing factor, Luforan, Lutrefact, Gonadoliberin I, Gonadotropin-releasing factor, Gonadoreline, p-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2, Gonadorelin decapeptide, Fertiral lh-rh, Relefact lh-rh, Fertelin, OvaCyst, Hypocrine, Luteostimulin, Dirigestran, Relefact, Glycinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-L-prolyl-, Nialutin, Lutal, Relisorm l, Mammalian GnRH, Synthetic LRF, Dirigestran Spofa, Synthetic Gn-RH, Mammalian LH-RH, Synthetic LH-RF, Synthetic LH-RH, Porchine LH-RH, Human LH-RH, Ovine LH-RH, LH-RH (swine), Synthetic gonadoliberin, Synthetic LH-FSH-RH, Human luteinizing hormone, Synthetic LH-RH/FSH-RH, LH-Releasing factor (pig), Porcine LH-releasing factor, Synthetic LH-releasing factor, Synthetic decapeptide FSH/LH-RH, Human gonadoliberin-i, Luteinizing hormone-areleasing factor (swine), L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-L-prolylglycinamide
- Cat. No.
- P-G056-006
- CAS
- 33515-09-2
- Alternative CAS
- 71447-49-9 (acetate)
- 51952-41-1 (hydrochloride)
- 51952-40-0 (hydrochloride)
- 52699-48-6 (acetate)
- 34973-08-5 (acetate)
- 499785-55-6 (acetate)
- Formula
- C55H75N17O13
- Molecular weight
- 1182.31 g/mol
- Category
- Active ingredient (API)
Family: Gonadorelin
A synthetic version of GnRH, the ten-amino-acid hormone through which the hypothalamus triggers the release of LH and FSH; its identity was clarified by Andrew Schally and Roger Guillemin, Nobel laureates in 1977. It is also used in veterinary medicine, for example for ovarian cysts in cattle.
Did you know?The hypothalamus releases it in pulses rather than continuously: the pulse frequency decides whether the pituitary releases mainly FSH (slow pulses) or LH (fast pulses).
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
Shipped under controlled temperature when the molecule requires it.
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Sent with every order.
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Gonadorelin for NMR identification CRSEP Y0001546
More products in the Gonadorelin family
Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
