Active ingredientHistamineCat. No. P-H021-001CAS 51-45-6
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Active ingredient · Histamine family
Pharmaceutical analytical standardHistamine Dihydrochloride
Synonyms: Histamine DiHCl, Peremin, Ceplene, Histaminum hydrochloricum, Maxamine, Pain Relieving Arthritis, Australian Dream Back Pain, CVS Arthritis Pain Relief, Histaminum Hydrochloricum 30X, Histaminum Hydrochloricum 200ck, Minted Leaf Odorless Pain Relief, Bakers Best Arthritis Pain Relief, Dr. Freds Miracle Rub, Edihydrochlorideavailablefrom1kgto100kg.
- Cat. No.
- P-H021-002
- CAS
- 56-92-8
- Alternative CAS
- 51-45-6 (free base)
- 117932-92-0 (free base)
- 65592-96-3 (free base)
- 55-36-7 (hydrochloride)
- 23758-34-1 (hydrochloride)
- 50743-03-8 (dihydrobromide)
- 51-74-1 (phosphate)
- Formula
- C5H9N3·2HCl
- Molecular weight
- 184.06 g/mol
- Category
- Active ingredient (API)
Family: Histamine
A biogenic amine made by mast cells and basophils: it drives allergy, inflammation and itch, stimulates stomach acid and keeps the brain awake. Its properties were described in 1910 by the British scientists Henry Dale and Patrick Laidlaw.
Did you know?Its name means 'tissue amine': although made of only 17 atoms, it takes part in about 23 functions of the body.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Histamine dihydrochloride CRSEP H0600000
- Histamine for system suitability CRSEP Y0002575
More products in the Histamine family
Active ingredientHistamineCat. No. P-H021-001CAS 51-45-6
Active ingredientHistamine PhosphateCat. No. P-H021-003CAS 51-74-1
Isotopically labelled1-Methyl-d3-1H-Imidazol-4-yl Acetic AcidCat. No. P-H021-004CAS 122380-33-0
Isotopically labelledHistamine-d4 DihydrochlorideCat. No. P-H021-005CAS 344299-48-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.