Active ingredientTipelukastCat. No. P-T130-001CAS 125961-82-2
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Stable isotope labelled · Tipelukast family
Pharmaceutical analytical standardHydroxy Tipelukast-d6 Sodium Salt
Synonyms: Hydroxy Tipelukast-d6 (sodium)
- Cat. No.
- P-T130-003
- CAS
- N/A
- Alternative CAS
- 1027597-04-1 (unlabelled form)
- Formula
- C29H33D6NaO7S
- Molecular weight
- 560.71 g/mol
- Category
- Stable isotope labelled
Family: Tipelukast
An experimental oral molecule that blocks leukotriene receptors, mediators of inflammation: studied first in asthma and then in idiopathic pulmonary fibrosis, for which it received orphan drug designation in the United States in 2014.
Did you know?It does not hit just one target: besides leukotriene receptors it also acts on phosphodiesterases and on 5-lipoxygenase, the enzyme that produces leukotrienes in the first place.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Tipelukast family
Active ingredientTipelukastCat. No. P-T130-001CAS 125961-82-2
Isotopically labelledHydroxy Tipelukast-d6Cat. No. P-T130-002
Isotopically labelledTipelukast-d6Cat. No. P-T130-004
ImpurityHydroxy TipelukastCat. No. P-T130-005CAS 1027597-04-1
ImpurityHydroxy Tipelukast Sodium SaltCat. No. P-T130-006Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.