Active ingredientImipenemCat. No. P-I032-001CAS 64221-86-9
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Impurity or related compound · Imipenem family
Pharmaceutical analytical standardImipenem Impurity 12
Synonyms: 3-[2-[2-[[2-Carboxy-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]sulfanyl]ethyliminomethylamino]ethylsulfanyl]-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
- Cat. No.
- P-I032-020
- CAS
- 85604-01-9
- Alternative CAS
- N/A
- Formula
- C23H30N4O8S2
- Molecular weight
- 554.63 g/mol
- Category
- Impurity or related compound
Family: Imipenem
A very broad-spectrum beta-lactam antibiotic of the carbapenem family, developed in the mid-1970s and approved in 1985 for serious infections; it is given with cilastatin, which stops the kidneys from breaking it down.
Did you know?It derives from thienamycin, made by the soil bacterium Streptomyces cattleya: too unstable in water to become a medicine, it was turned into imipenem after lengthy trial and error.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Imipenem family
Active ingredientImipenemCat. No. P-I032-001CAS 64221-86-9
Pharmacopoeial impurityImipenem EP Impurity ACat. No. P-I032-003CAS 59995-64-1
Pharmacopoeial impurityImipenem EP Impurity B (90%)Cat. No. P-I032-004CAS 1197869-90-1
Isotopically labelledImipenem-d4Cat. No. P-I032-005CAS 1261396-26-2
ImpurityImipenem Cilastatin DimerCat. No. P-I032-006
ImpurityImipenem DimerCat. No. P-I032-007
ImpurityImipenem Impurity 1Cat. No. P-I032-009
ImpurityImipenem Impurity 2Cat. No. P-I032-010Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.