Active ingredientIohexolCat. No. P-I058-001CAS 66108-95-0
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Impurity or related compound · Iohexol family
Pharmaceutical analytical standardIohexol Impurity 3
Synonyms: 5-Amino-3-N-(1,3-dihydroxypropan-2-yl)-1-N-(2,3-dihydroxypropyl)benzene-1,3-dicarboxamide
- Cat. No.
- P-I058-028
- CAS
- 267881-77-6
- Alternative CAS
- N/A
- Formula
- C14H21N3O6
- Molecular weight
- 327.34 g/mol
- Category
- Impurity or related compound
Family: Iohexol
A low-osmolality non-ionic iodinated contrast agent, developed in Norway and introduced in the mid-1980s: it makes blood vessels, organs and the spinal canal visible in X-ray, CT and angiography.
Did you know?The idea of non-ionic contrast agents came to Swedish radiologist Torsten Almén: salty seawater stung his eyes while the brackish water near Ystad did not, and he guessed that the pain depended on osmolality.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Iohexol family
Active ingredientIohexolCat. No. P-I058-001CAS 66108-95-0
Pharmacopoeial impurityIohexol EP Impurity ACat. No. P-I058-002CAS 31127-80-7
Pharmacopoeial impurityIohexol EP Impurity B (Mixture of Diastereomers)Cat. No. P-I058-003CAS 2732209-64-0
Pharmacopoeial impurityIohexol EP Impurity C (Mixture of Diastereomers)Cat. No. P-I058-004CAS 2724765-15-3
Pharmacopoeial impurityIohexol EP Impurity D (Mixture of Diastereomers)Cat. No. P-I058-005CAS 157739-09-8
Pharmacopoeial impurityIohexol EP Impurity E (Mixture of Diastereomers)Cat. No. P-I058-006CAS 2727061-52-9
Pharmacopoeial impurityIohexol EP Impurity F (2,4-diiodo Isomer)Cat. No. P-I058-007CAS 1215856-35-1
Pharmacopoeial impurityIohexol EP Impurity F HCl (4,6-diiodo Isomer)Cat. No. P-I058-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.