Active ingredientKetamine HydrochlorideCat. No. P-K003-001CAS 1867-66-9
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Pharmacopoeial impurity · Ketamine family
Pharmaceutical analytical standardKetamine EP Impurity A (E-Isomer) HCl
Synonyms: Ketamine USP Related Compound A (E-Isomer) HCl
- Cat. No.
- P-K003-003
- CAS
- N/A
- Alternative CAS
- 90717-16-1 (other form)
- Formula
- C13H16ClNO·HCl
- Molecular weight
- 274.19 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Ketamine
A dissociative anaesthetic synthesised in 1962 by chemist Calvin Stevens and approved in the United States in 1970. It depresses breathing much less than other anaesthetics, which makes it valuable in emergencies, paediatrics and veterinary medicine, and it is on the WHO list of essential medicines.
Did you know?The expression 'dissociative anaesthetic' was coined by Toni Domino, wife of pharmacologist Edward Domino, one of the researchers who carried out the first human tests in 1964.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Ketamine family
Active ingredientKetamine HydrochlorideCat. No. P-K003-001CAS 1867-66-9
Pharmacopoeial impurityKetamine EP Impurity ACat. No. P-K003-002CAS 6740-87-0
Pharmacopoeial impurityKetamine Hydrochloride EP Impurity BCat. No. P-K003-004CAS 1823362-29-3
Pharmacopoeial impurityKetamine Hydrochloride EP Impurity CCat. No. P-K003-005CAS 90717-17-2
Pharmacopoeial impurityKetamine USP Related Compound A (Z-isomer) HClCat. No. P-K003-006CAS 90717-16-1
Isotopically labelledDehydro Norketamine-d4Cat. No. P-K003-007CAS 1246816-68-1
Isotopically labelledKetamine-d4 HydrochlorideCat. No. P-K003-008CAS 1246815-97-3
Isotopically labelledNorketamine-d4Cat. No. P-K003-009CAS 1286586-83-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.