Active ingredientLeucineCat. No. P-L039-001CAS 61-90-5
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Impurity or related compound · Leucine family
Pharmaceutical analytical standardL-tert-Leucine
Synonyms: NSC 203785, L-valine,3-methyl, H-TLE-OH, H-tert-Leu-OH, Valine, 3-methyl-, L-tert-butylglycine, L-tertiary leucine, tert-Leu-OH, L-a-tert-Butylglycine, t-leucine, l-t-butylglycine, h-l-tle-oh
- Cat. No.
- P-L039-023
- CAS
- 20859-02-3
- Alternative CAS
- N/A
- Formula
- C6H13NO2
- Molecular weight
- 131.18 g/mol
- Category
- Impurity or related compound
Family: Leucine
An essential branched-chain amino acid, like valine and isoleucine: the body cannot make it and must obtain it from the diet. It activates the mTOR signalling pathway, which controls protein synthesis in muscle.
Did you know?The first sample was obtained by Proust in 1819 while studying the flavour of cheese; a year later Henri Braconnot isolated it from muscle fibre and named it leucine from the Greek leukos, white, after the colour of its crystals.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Leucine family
Active ingredientLeucineCat. No. P-L039-001CAS 61-90-5
NitrosamineN-Nitroso N-Formyl-L-LeucineCat. No. P-L039-002
ImpurityD-Leucine Methyl Ester HydrochlorideCat. No. P-L039-003CAS 5845-53-4
ImpurityDL-LeucineCat. No. P-L039-004CAS 328-39-2
ImpurityFmoc-alphamethyl LeucineCat. No. P-L039-005CAS 312624-65-0
ImpurityLevacetylleucineCat. No. P-L039-006CAS 1188-21-2
ImpurityN-alpha-formyl-d-leucineCat. No. P-L039-007CAS 44978-39-4
ImpurityN-MethylleucineCat. No. P-L039-010CAS 3060-46-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.