Active ingredient · Lapachol family
Pharmaceutical analytical standardLapachol
Synonyms: 4-hydroxy-3-(3-methylbut-2-enyl)naphthalene-1,2-dione, Greenhartin, Bethabarra wood, Taiguic acid, Lapachic acid, C.I. Natural Yellow 16, Taigu wood, IPE-tobacco wood, Greenharten, Surinam greenheart wood, NSC 11905, Zlut prirodni 16, NSC 629756, Tecomin, Lapachoic acid, IMB-LA
- Cat. No.
- P-L016-001
- CAS
- 84-79-7
- Alternative CAS
- 57414-00-3 (sodium salt)
- Formula
- C15H14O3
- Molecular weight
- 242.27 g/mol
- Category
- Active ingredient (API)
A yellow naphthoquinone found in the wood and bark of lapacho trees (Handroanthus impetiginosus, formerly Tabebuia avellanedae), chemically related to vitamin K: in the past it was studied as a possible anticancer agent.
Did you know?It had been known since 1858, but it was the Palermo-born chemist Emanuele Paternò who elucidated its structure in 1882; Paternò was also mayor of Palermo and discovered the photochemical reaction that bears his name.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
Shipped under controlled temperature when the molecule requires it.
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Sent with every order.
Follow your shipment live, from our warehouse to your lab.
Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
