Isotopically labelled4-Hydroxy-3-methoxy Mandelic Acid-13C6Cat. No. P-M004-002CAS 1189690-96-7
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Pharmacopoeial impurity · Mandelic Acid family
Pharmaceutical analytical standardMandelic Acid
Synonyms: 2-hydroxy-2-phenylacetic acid, dl-Mandelic acid, Phenylglycolic acid, Paramandelic acid, Amygdalic acid, Uromaline, Racemic mandelic acid, Phenylhydroxyacetic acid, Kyselina mandlova, Benzeneacetic acid, alpha-hydroxy-, alpha-Hydroxybenzeneacetic acid, NSC 7925, alpha-Hydroxyphenylacetic acid, Almond acid, p-Mandelic acid, Hydroxy(phenyl)acetic acid, Glycolic acid, phenyl-, alpha-Hydroxy-alpha-toluic acid, DL-Hydroxy(phenyl)acetic acid, DL-Amygdalic Acid, Kyselina 2-fenyl-2-hydroxyethanova, alpha-Toluic acid, alpha-hydroxy-, alpha-hydroxybenzeneacetate, Benzoglycolic acid, Phenylacetic acid, alpha-hydroxy-, l(+)mandelic acid, SAMMA, Hyroxyphenylacetic acid, Benzeneacetic acid, alpha-hydroxy-, (alphaR)-, alpha-Phenylhydroxyacetic acid, Acetic acid, 2-hydroxy-2-phenyl-, Benzeneacetic acid, alpha-hydroxy-, (S)-, Mandelic Acid ((2RS)-2-Hydroxy-2-phenylacetic Acid)
- Cat. No.
- P-M004-004
- CAS
- 90-64-2
- Alternative CAS
- N/A
- Formula
- C8H8O3
- Molecular weight
- 152.15 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Mandelic Acid
An aromatic alpha hydroxy acid discovered in 1831 by the German pharmacist Ferdinand Ludwig Winckler: today it is used in superficial chemical peels and as a starting material for medicines such as homatropine.
Did you know?Its name comes from the German Mandel, almond: Winckler obtained it by heating amygdalin, extracted from bitter almonds, with dilute hydrochloric acid.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Pregabalin impurity C CRSEP Y0002556
More products in the Mandelic Acid family
Isotopically labelled4-Hydroxy-3-methoxy Mandelic Acid-13C6Cat. No. P-M004-002CAS 1189690-96-7
ImpurityEthyl MandelateCat. No. P-M004-003CAS 774-40-3Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.