ImpurityMebrofenin Impurity 1Cat. No. P-M020-002CAS 65717-98-8
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Active ingredient · Mebrofenin family
Pharmaceutical analytical standardMebrofenin
Synonyms: Glycine, N-(2-((3-bromo-2,4,6-trimethylphenyl)amino)-2-oxoethyl)-N-(carboxymethyl)-, N-(2-((3-Bromo-2,4,6-trimethylphenyl)amino)-2-oxoethyl)-N-(carboxymethyl)glycine, Choletec
- Cat. No.
- P-M020-001
- CAS
- 78266-06-5
- Alternative CAS
- N/A
- Formula
- C15H19BrN2O5
- Molecular weight
- 387.23 g/mol
- Category
- Active ingredient (API)
An iminodiacetic acid derivative that, bound to technetium-99m, allows the liver, gallbladder and bile ducts to be imaged by hepatobiliary scintigraphy; approved in the United States in 1987.
Did you know?Its structure resembles that of lidocaine, the local anaesthetic: in the diagnostic complex two of these molecules surround a technetium-99m atom, which is taken up almost entirely by the liver.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Mebrofenin CRSEP Y0001086
More products in the Mebrofenin family
ImpurityMebrofenin Impurity 1Cat. No. P-M020-002CAS 65717-98-8
ImpurityMebrofenin N-OxideCat. No. P-M020-003CAS 2724762-75-6
ImpurityMebrofenin Impurity 2Cat. No. P-M020-004CAS 119518-61-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.