Active ingredientMesna Sodium SaltCat. No. P-M064-001CAS 19767-45-4
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Stable isotope labelled · Mesna family
Pharmaceutical analytical standardMesna-d4 Sodium Salt
Synonyms: Mesna-d4 (may contain up to 10% disulfide), sodium 1,1,2,2-tetradeuterio-2-sulfanylethanesulfonate, Mesna-d4 (contain disulfide)
- Cat. No.
- P-M064-008
- CAS
- 1189479-73-9
- Alternative CAS
- 3375-50-6 (unlabelled form)
- 19767-45-4 (unlabelled form)
- 1190884-58-2 (free acid)
- 126397-51-1 (unlabelled form, potassium salt)
- Formula
- C2HD4NaO3S2
- Molecular weight
- 168.19 g/mol
- Category
- Stable isotope labelled
Family: Mesna
A sulphur compound (sodium 2-mercaptoethanesulfonate) approved in the United States in 1988: it protects the bladder during chemotherapy with ifosfamide and cyclophosphamide by binding and inactivating acrolein, an irritant metabolite.
Did you know?The name is an acronym of 2-MErcaptoethane Sulfonate NA (Na being the symbol for sodium); outside North America it is also used as a mucolytic, to thin mucus.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Mesna family
Active ingredientMesna Sodium SaltCat. No. P-M064-001CAS 19767-45-4
Pharmacopoeial impurityMesna EP Impurity CCat. No. P-M064-002CAS 69536-71-6
Pharmacopoeial impurityMesna EP Impurity DCat. No. P-M064-003CAS 45127-11-5
Pharmacopoeial impurityMesna EP Impurity ACat. No. P-M064-004CAS 25985-57-3
Pharmacopoeial impurityMesna EP Impurity BCat. No. P-M064-005CAS 1391053-66-9
Pharmacopoeial impurityMesna EP Impurity ECat. No. P-M064-006CAS 1391054-56-0
Pharmacopoeial impurityMesna EP Impurity E Sodium SaltCat. No. P-M064-007
ImpurityMesna Impurity 1 Sodium SaltCat. No. P-M064-009CAS 1110574-95-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.