Active ingredientMethyldopa SesquihydrateCat. No. P-M093-002CAS 41372-08-1
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Active ingredient · Methyldopa family
Pharmaceutical analytical standardMethyldopa
Synonyms: Methyldopum, Dopamet, Presolisin, Medomet, Alpha medopa, Aldometil, Methoplain, Sedometil, Dopatec, Hyperpax, alpha-Methyl dopa, Sembrina, Hypolag, Dopegyt, Medopren, Presinol, alpha-Methyl-L-dopa, L-Methyl Dopa, Metildopa, L-(alpha-Md), Methyl-L-dopa, Dopegit, Aldomin, Lederdopa, alpha-Methyldihydroxyphenylalanine, alpha-Methyl-L-3,4-dihydroxyphenylalanine, L-alpha-Methyl-3,4-dihydroxyphenylalanine, L-(-)-3-(3,4-Dihydroxyphenyl)-2-methylalanine, alpha-Methyl-beta-(3,4-dihydroxyphenyl)-L-alanine, L(-)-beta-(3,4-Dihydroxyphenyl)-alpha-methylalanine, L-(-)-alpha-Methyl-beta-(3,4-dihydroxyphenyl)alanine, L-Tyrosine, 3-hydroxy-alpha-methyl-, NSC 169916, NSC 760080, Alanine, 3-(3,4-dihydroxyphenyl)-2-methyl-, L-(-)-, Dopergit, Amodopa, Nu Medopa, Metalpha 250, Metalpha 500, Baypresol, Aldomet, L-alpha-Methyl DOPA, Dopamethyperpax, Grospisk, Becanta, Medopal, Novomedopa, a-methyl-l-dopa, alpha-Methyl-L-dopa sesquihydrate, Phenylalanine, alpha-methyl-3,4-dihydroxy-, Medoba, a-methyl dopa, Tyrosine, 3-hydroxy-alpha-methyl-, L(-)-a-methylalanine, Nu-Medopa Tab 125mg, Nu-Medopa Tab 250mg, Nu-Medopa Tab 500mg, L(-)-alpha-methylalanine, Pharmakon1600-01500403, L-(-)-a-methyl-a-methyl-Aldomin, a-Methyl-L-3,4-dihydroxyphenylalanine, L-(-)-alpha-methyl-alpha-methyl-Aldomin, L-a-Methyl-(3, 4-dihydroxyphenyl)alanine, l-alpha-methyl-3-(3,4)-dihydroxyphenylalanine
- Cat. No.
- P-M093-001
- CAS
- 555-30-6
- Alternative CAS
- 884-39-9 (hydrochloride)
- 41372-08-1 (hydrate)
- 88620-56-8 (alternative CAS, same compound)
- 27289-76-5 (alternative CAS, same compound)
- Formula
- 2C10H13NO4·3H2O
- Molecular weight
- 476.48 g/mol
- Category
- Active ingredient (API)
A centrally acting antihypertensive, an alpha-2 adrenergic receptor agonist, discovered in 1960; it is still one of the preferred drugs for high blood pressure in pregnancy.
Did you know?It is a 'false precursor': in the brain it is converted into alpha-methylnoradrenaline, which activates alpha-2 receptors and curbs the release of the nerve signals that raise blood pressure.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- MethyldopaBP 240
More products in the Methyldopa family
Active ingredientMethyldopa SesquihydrateCat. No. P-M093-002CAS 41372-08-1
Pharmacopoeial impurityMethyldopa EP Impurity ACat. No. P-M093-003CAS 6739-31-7
Pharmacopoeial impurityMethyldopa EP Impurity B HClCat. No. P-M093-004CAS 35026-10-9
Pharmacopoeial impurityMethyldopa EP Impurity CCat. No. P-M093-005CAS 39948-18-0
Pharmacopoeial impurityMethyldopa EP Impurity C HClCat. No. P-M093-006CAS 5486-79-3
Pharmacopoeial impurityMethyldopa EP Impurity C HCl H2OCat. No. P-M093-007
Pharmacopoeial impurityMethyldopa EP Impurity DCat. No. P-M093-008CAS 2799-15-7
Pharmacopoeial impurityMethyldopa EP Impurity D HClCat. No. P-M093-009CAS 1369423-51-7Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.