Active ingredientMethylphenidate HydrochlorideCat. No. P-M096-001CAS 298-59-9
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Impurity or related compound · Methylphenidate family
Pharmaceutical analytical standardMethylphenidate Impurity 3
Synonyms: trans-7-Phenyl-1-azabicyclo[4.2.0]octan-8-one
- Cat. No.
- P-M096-031
- CAS
- 403502-85-2
- Alternative CAS
- N/A
- Formula
- C13H15NO
- Molecular weight
- 201.27 g/mol
- Category
- Impurity or related compound
Family: Methylphenidate
A central nervous system stimulant synthesised in 1944 in Basel by chemist Leandro Panizzon and licensed in the United States in 1955. It is used for attention deficit hyperactivity disorder (ADHD) and narcolepsy.
Did you know?Panizzon tried it on himself and on his wife Marguerite, whom he called Rita: she played tennis and found it helped her on the court. The medicine was later named after her nickname.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Methylphenidate family
Active ingredientMethylphenidate HydrochlorideCat. No. P-M096-001CAS 298-59-9
Pharmacopoeial impurityMethylphenidate EP Impurity A HydrochlorideCat. No. P-M096-002CAS 1382859-13-3
Pharmacopoeial impurityMethylphenidate EP Impurity CCat. No. P-M096-004CAS 50288-62-5
Pharmacopoeial impurityMethylphenidate EP Impurity DCat. No. P-M096-005CAS 50288-63-6
Pharmacopoeial impurityMethylphenidate EP Impurity E HydrochlorideCat. No. P-M096-006CAS 19716-79-1
Pharmacopoeial impurityMethylphenidate EP Impurity ECat. No. P-M096-007CAS 99088-55-8
Pharmacopoeial impurityMethylphenidate EP Impurity FCat. No. P-M096-008CAS 7251-52-7
Isotopically labelledMethylphenidate-d9 HydrochlorideCat. No. P-M096-009CAS 1219908-85-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.