Active ingredientMitomycinCat. No. P-M146-001CAS 50-07-7
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Impurity or related compound · Mitomycin family
Pharmaceutical analytical standardMitomycin Impurity 5 (Mixture of Diastereomers)
- Cat. No.
- P-M146-019
- CAS
- 151797-98-7
- Alternative CAS
- N/A
- Formula
- C28H31N7O7
- Molecular weight
- 577.60 g/mol
- Category
- Impurity or related compound
Family: Mitomycin
An antitumour antibiotic produced by the soil bacterium Streptomyces caespitosus, isolated in Japan in the mid-1950s: it cross-links the two strands of DNA, preventing it from copying itself, and is used against several cancers.
Did you know?It also has a role in eye surgery: applied during operations for glaucoma or pterygium, it curbs the formation of the scar tissue that would spoil the result.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Mitomycin family
Active ingredientMitomycinCat. No. P-M146-001CAS 50-07-7
Pharmacopoeial impurityMitomycin EP Impurity BCat. No. P-M146-002CAS 4055-39-4
Isotopically labelledMitomycin C-13C-d3Cat. No. P-M146-003
Isotopically labelledMitomycin C-D3Cat. No. P-M146-004
NitrosamineN-Nitroso Mitomycin CCat. No. P-M146-005
Pharmacopoeial impurityMitomycin EP Impurity ACat. No. P-M146-006CAS 22031-64-7
Impuritytrans-1-Hydroxy-2,7-diamino MitoseneCat. No. P-M146-007CAS 99745-88-7
Impurity10-Decarbamoyl Mitomycin CCat. No. P-M146-008CAS 26909-37-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.