Active ingredientMoxidectinCat. No. P-M174-001CAS 113507-06-5
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Pharmacopoeial impurity · Moxidectin family
Pharmaceutical analytical standardMoxidectin EP Impurity J
Synonyms: 7-O-((methylsulfanyl)methyl)moxidectin, Moxidectin impurity j
- Cat. No.
- P-M174-011
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C39H57NO8S
- Molecular weight
- 699.94 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Moxidectin
A semisynthetic antiparasitic of the milbemycin family, used in veterinary medicine since 1990 and approved in the United States in 2018 for onchocerciasis, the "river blindness" caused by a worm spread by blackflies, from 12 years of age.
Did you know?The bacterium that yields its parent molecule, Streptomyces cyanogriseus, was discovered in an Australian soil sample; and in Australia the drug is also used to treat mange in wombats.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Moxidectin family
Active ingredientMoxidectinCat. No. P-M174-001CAS 113507-06-5
Pharmacopoeial impurityMoxidectin EP Impurity ACat. No. P-M174-002CAS 114041-32-6
Pharmacopoeial impurityMoxidectin EP Impurity BCat. No. P-M174-003
Pharmacopoeial impurityMoxidectin EP Impurity CCat. No. P-M174-004CAS 114041-23-5
Pharmacopoeial impurityMoxidectin EP Impurity DCat. No. P-M174-005
Pharmacopoeial impurityMoxidectin EP Impurity ECat. No. P-M174-006CAS 2482741-71-7
Pharmacopoeial impurityMoxidectin EP Impurity FCat. No. P-M174-007
Pharmacopoeial impurityMoxidectin EP Impurity GCat. No. P-M174-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.