Active ingredientProtriptylineCat. No. P-P227-001CAS 438-60-8
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Nitrosamine · Protriptyline family
Pharmaceutical analytical standardN-Nitroso Protriptyline
- Cat. No.
- P-P227-005
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C19H20N2O
- Molecular weight
- 292.38 g/mol
- Category
- Nitrosamine
Family: Protriptyline
A tricyclic antidepressant with a dibenzocycloheptene structure, patented in 1962 and introduced in 1966 for depression, including when it comes with anxiety.
Did you know?Unlike most tricyclics it does not cause drowsiness but tends to be energising: it is the least sedating of its class and has also been used in narcolepsy to promote wakefulness.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Protriptyline family
Active ingredientProtriptylineCat. No. P-P227-001CAS 438-60-8
Active ingredientProtriptyline HydrochlorideCat. No. P-P227-002CAS 1225-55-4
Isotopically labelledProtriptyline-d3Cat. No. P-P227-003CAS 136765-50-9
Isotopically labelledProtriptyline-d6Cat. No. P-P227-004
ImpurityProtriptyline-10,11-dihydrodiolCat. No. P-P227-006CAS 29785-65-7
Impurity10-Hydroxy ProtriptylineCat. No. P-P227-007
ImpurityProtriptyline-10,11-EpoxideCat. No. P-P227-008CAS 55698-64-1
ImpurityProtriptyline-N-OxideCat. No. P-P227-009Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.