Active ingredientNicotine BenzoateCat. No. P-N052-002CAS 88660-53-1
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Active ingredient · Nicotine family
Pharmaceutical analytical standardNicotine
Synonyms: 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine, Habitrol, Nicotrol, Nicoderm, Nicoderm Cq, Fumetobac, Prostep, Tendust, Nico-dust, Emo-nik, Nico-Fume, Mach-Nic, Nic-Sal, Flux MAAG, Nikotyna, Ortho N-4 dust, Ortho N-5 dust, XL All Insecticide, Niagara P.A. dust, Nicocide, Black Leaf 40, Nicabate, Niquitin, Tabazur, Black leaf, beta-Pyridyl-alpha-N-methylpyrrolidine, Nikotin, Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)-, Pyrrolidine, 1-methyl-2-(3-pyridal)-, Pyridine, 3-(tetrahydro-1-methylpyrrol-2-yl), Pyridine, 3-((2S)-1-methyl-2-pyrrolidinyl)-, NSC 5065, Blip, Nicorelief, Nicopass, Nicopatch, Stoppers, Stubit, Nictoine gum, Niquitin mint, NicFix, Nicorette Mint, Niquitin clr, Nicorette invisi, Good Sense, Habitrol Lozenge, NicFix Plus, Habitrol Step 1, Habitrol Step 2, Habitrol Step 3, Niquitin pre-quit, Stop Smoking Aid, Nicorette Original, Niquitin minis mint, Niquitin strips mint, Niquitin minis cherry, Niquitin minis orange, Nicorette Fruit Chill, Habitrol Lozenge Cherry, Nicorette Cinnamon Surge, Nicorette Spearmint Burst, Nicorette White Ice Mint, Kirkland Signature Quit 2, Kirkland Signature Quit 4, Nicorette 4mg Cinnamon Surge, Habitrol Lozenge Original Flavor, Nicorette 4mg Fruit Chill Gum, Lil Drug Store, Nicorette 4mg White Ice Mint Gum, Lil Drug Store, Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, Micotine, Pyrrolidine, 1-methyl-2-(3-pyridyl)-, Nicotrol Inhaler, Nicotrol NS, Destruxol, Caswell No. 597, EPA Pesticide Chemical Code 056702, Campbell's nico-soap
- Cat. No.
- P-N052-001
- CAS
- 54-11-5
- Alternative CAS
- 65-30-5 (sulfate)
- 2820-51-1 (hydrochloride)
- 21361-93-3 (hydrochloride)
- 6019-02-9 (dihydrochloride)
- 5153-64-0 (acetate)
- 73057-36-0 (malate)
- 6019-06-3 (tartrate hydrate)
- 65-31-6 (tartrate)
- Formula
- C10H14N2
- Molecular weight
- 162.24 g/mol
- Category
- Active ingredient (API)
An alkaloid from the tobacco plant, Nicotiana tabacum, isolated in 1828 by German chemists Posselt and Reimann. It stimulates nicotinic receptors in the nervous system and, as a medicine, is used in patches, gums and lozenges to help people stop smoking.
Did you know?The name honours Jean Nicot, French ambassador to Portugal, who in 1560 introduced tobacco to the French court, convinced of its medicinal virtues.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Nicotine family
Active ingredientNicotine BenzoateCat. No. P-N052-002CAS 88660-53-1
Active ingredientNicotine MalateCat. No. P-N052-003CAS 73057-36-0
Pharmacopoeial impurity(S)-Anabasine DiHClCat. No. P-N052-004CAS 31945-06-9
Pharmacopoeial impurityNicotine EP Impurity A (as Racemate)Cat. No. P-N052-005CAS 2743-90-0
Pharmacopoeial impurityNicotine EP Impurity BCat. No. P-N052-006CAS 487-19-4
Pharmacopoeial impurityNicotine EP Impurity CCat. No. P-N052-007CAS 486-56-6
Pharmacopoeial impurityNicotine EP Impurity DCat. No. P-N052-008CAS 532-12-7
Pharmacopoeial impurityNicotine EP Impurity ECat. No. P-N052-009CAS 491-26-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.