Immunology peptides
PADRE Peptide AKFVAAWTLKAAA
Synthetic PADRE peptide AKFVAAWTLKAAA, a T helper epitope with broad HLA-DR binding
- Cat. No.
- P2284
- Category
- Immunology peptides
- Formats
- 2 formats
- Manufacturer
PADRE is a synthetic 13-amino acid peptide, sequence AKFVAAWTLKAAA, that acts as a T helper epitope with broad (pan-HLA-DR) binding to HLA-DR molecules. It is studied as a component for developing synthetic and recombinant vaccines, for example in constructs with beta-amyloid peptides in mouse models. It is supplied lyophilised, without additives, at a purity above 95% (HPLC, ESI-MS).
Key features
Pan-HLA-DR epitope
Binds broadly to HLA-DR molecules and acts as a T helper epitope.
Vaccine research
Used as a helper epitope in the development of synthetic and recombinant vaccines.
Verified quality
Purity above 95% checked by HPLC and ESI-MS.
Easy reconstitution
Soluble in water or water/methanol 1:1 for 1 mg/mL stock solutions.
Applications
- Development of synthetic and recombinant vaccines
- Enhancing CD4+ T helper responses
- Experimental vaccine constructs, e.g. with beta-amyloid
- T-cell epitope studies
Technical details
| Sequence | AKFVAAWTLKAAA (Ala-Lys-Phe-Val-Ala-Ala-Trp-Thr-Leu-Lys-Ala-Ala-Ala) |
|---|---|
| Binding | Pan-HLA-DR |
| Molecular weight | 1347.6 g/mol |
| Formula | C65H102N16O15 |
| Purity | > 95% (HPLC, ESI-MS) |
| Appearance | Lyophilised powder, no additives |
| Reconstitution | Water or water/methanol (1:1), 1 mg/mL stock |
| Storage | -20 °C; after reconstitution aliquot and store at or below -20 °C, avoiding freeze-thaw cycles |
| Shipping | Ambient temperature |
What you receive
The product
Shipped under controlled temperature when the product requires it.
Lot certificate
Every lot comes with its certificate.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
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Frequently asked questions
Can I ask for formats other than those listed?
Yes: custom formats and OEM packs are available on request. Tell us the quantities you need.
How do I see the prices?
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How long does delivery take?
We give you the availability with the quote, within 24 hours of your request.