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Phenolphthalein
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Highly Characterized Analytical Standard

Active ingredient · Phenolphthalein family

Pharmaceutical analytical standard

Phenolphthalein

Synonyms: 3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one, Phthalimetten, Euchessina, Phenolax, Phthalin, Purgophen, Espotabs, Laxogen, Koprol, Purga, Trilax, Spulmako-lax, Chocolax, Purgen, Dihydroxyphthalophenone, Phenolphtaleine, Correctol, Medilax, Colax, Laxin, FemiLax, Fenolftalein, Fenolftaleina, alpha-Di(p-hydroxyphenyl)phthalide, NSC 10464, Laxettes, Ex-Lax, o-Toluic acid, alpha-(p-hydroxyphenyl)-alpha-4-oxo-2,5-cyclohexadien-1-ylidene-, Prulet, Alophen, Phillips Gelcaps, Phenophthalein, Feen-A-Mint Laxative Mints, Component of Agoral, Phthalide 3,3,-bis(p-hydroxyphenyl)-, Evac-Q-Kwik, Evac-U-Gen, Component of Correctol, Agoral, Phthalide 3,-bis(p-hydroxyphenyl)-, Phenolphtalein, Modane, alpha-(p-Hydroxyphenyl)-alpha-(4-oxo-2,5-cyclohexadien-1-ylidene)-o-toluic acid, Pharmakon1600-01500480, NSC 215214, NSC 757271, Alpha, alpha-Di(p-hydroxyphenyl)phthalide

Cat. No.
P-P080-001
CAS
77-09-8
Alternative CAS
  • 128734-39-4 (potassium salt)
  • 60195-00-8 (phosphate)
Formula
C20H14O4
Molecular weight
318.33 g/mol
Category
Active ingredient (API)

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Characterisation level

* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.

Quantity
Talk to a specialist

We reply within 24 hours with a quote and availability. CoA and SDS with every lot.

A dye of the phthalein family discovered in 1871 by Adolf von Baeyer: colourless in acid, it turns pink to fuchsia in alkaline solutions and is the classic indicator for titrations. For much of the 20th century it was also used as a laxative.

Did you know?Its laxative effect was discovered by chance in 1900, when the Hungarian government tried adding it to white wine as a marker: the taste did not change, but drinkers soon noticed.

The two levels compared

Level 1
Mass balance
Level 2
Mass balance + qNMR
Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR)✓✓
HPLC purity (min. 95%)✓✓
Content by mass balance (min. 90%; peptides: for information only)*✓✓
Content verified by qNMR (small molecules only)·✓
Suitable to qualify it as an in-house primary standard (ICH Q7)·✓

* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.

What you receive

The analytical standard

Shipped under controlled temperature when the molecule requires it.

Certificate of analysis (CoA)

For every lot: identity, purity and assay, with the supporting spectra and chromatograms.

Safety data sheet (SDS)

Sent with every order.

Tracked shipment

Follow your shipment live, from our warehouse to your lab.

More products in the Phenolphthalein family

See all 2 products in the family

Frequently asked questions

Is mass balance always performed?

Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.

Can I ask for a different quantity?

Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.

Which level should I choose?

Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.

When will I get the quote?

Within 24 working hours, with price, availability and delivery time.

Need a molecule you cannot find?

Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.