ImpurityEserine HemisulfateCat. No. P-P103-003CAS 64-47-1
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Impurity or related compound · Physostigmine family
Pharmaceutical analytical standardPhysostigmine Salicylate
Synonyms: Isopto Eserine, Physostigmine monosalicylate, Physostigmini salicylas, NSC 757275, Anticholium, Pyrrolo(2,3-b)indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, methylcarbamate (ester), (3aS-cis)-, mono(2-hydroxybenzoate), Physostol salicylate, Antilirium, Pharmakon1600-01500486, Physostigmine salicylate (JAN/USP)
- Cat. No.
- P-P103-004
- CAS
- 57-64-7
- Alternative CAS
- 57-47-6 (free base)
- 64-47-1 (sulfate)
- Formula
- C15H21N3O2·C7H6O3
- Molecular weight
- 413.47 g/mol
- Category
- Impurity or related compound
Family: Physostigmine
An alkaloid of the Calabar bean (Physostigma venenosum), a climbing legume of tropical Africa: a reversible cholinesterase inhibitor, used against glaucoma since 1876 and today also as an antidote in anticholinergic poisoning.
Did you know?Its other name, eserine, comes from éséré, the local name of the bean; in 1935 chemists Percy Lavon Julian and Josef Pikl achieved its first total synthesis.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Physostigmine salicylate CRSEP P1600000
More products in the Physostigmine family
ImpurityEserine HemisulfateCat. No. P-P103-003CAS 64-47-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
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