Active ingredientPindololCat. No. P-P117-001CAS 13523-86-9
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Pharmacopoeial impurity · Pindolol family
Pharmaceutical analytical standardPindolol EP Impurity F
Synonyms: 1-Chloro-3-(1H-indol-4-yloxy)-2-propanol, 1-chloro-3-(1H-indol-4-yloxy)propan-2-ol, Pindolol impurity f (ep impurity), Pindolol impurity F
- Cat. No.
- P-P117-007
- CAS
- 130115-66-1
- Alternative CAS
- N/A
- Formula
- C11H12ClNO2
- Molecular weight
- 225.67 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Pindolol
A non-selective beta blocker with intrinsic sympathomimetic activity, patented in 1969: it is used for high blood pressure and, in several countries, for angina pectoris and some arrhythmias.
Did you know?It also blocks serotonin 5-HT1A autoreceptors, which normally hold back serotonin release: for this reason it has been studied as an aid to boost some antidepressants, with mixed results.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Pindolol family
Active ingredientPindololCat. No. P-P117-001CAS 13523-86-9
Pharmacopoeial impurityPindolol EP Impurity ACat. No. P-P117-002
Pharmacopoeial impurityPindolol EP Impurity BCat. No. P-P117-003CAS 130115-63-8
Pharmacopoeial impurityPindolol EP Impurity CCat. No. P-P117-004CAS 130115-65-0
Pharmacopoeial impurityPindolol EP Impurity DCat. No. P-P117-005CAS 61212-32-6
Pharmacopoeial impurityPindolol EP Impurity ECat. No. P-P117-006CAS 2380-94-1
Isotopically labelledPindolol-d7Cat. No. P-P117-008CAS 1185031-19-9
NitrosamineN1-Nitroso PindololCat. No. P-P117-009Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.