Active ingredientPropofolCat. No. P-P217-001CAS 2078-54-8
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Pharmacopoeial impurity · Propofol family
Pharmaceutical analytical standardPropofol EP Impurity D
Synonyms: 2,5-Diisopropylphenol, 2,5-di(propan-2-yl)phenol, Phenol, 2,5-bis(1-methylethyl)-, Propofol impurity d (ep impurity), Propofol Impurity D
- Cat. No.
- P-P217-006
- CAS
- 35946-91-9
- Alternative CAS
- N/A
- Formula
- C12H18O
- Molecular weight
- 178.28 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Propofol
A fast-acting intravenous anaesthetic used to induce and maintain general anaesthesia and for sedation. Its properties were discovered by John Glen in the United Kingdom in 1973; it reached the operating theatre in 1986.
Did you know?Its milky white look, due to the soybean oil emulsion that makes it injectable, and how little patients remember afterwards earned it the nickname 'milk of amnesia'. In 2018 John Glen received the Lasker Award.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
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Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.