Active ingredientPyronaridineCat. No. P-P241-001CAS 74847-35-1
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Stable isotope labelled · Pyronaridine family
Pharmaceutical analytical standardPyronaridine-13C2-d4 Tetraphosphate
- Cat. No.
- P-P241-004
- CAS
- N/A
- Alternative CAS
- 1261393-31-0 (free base)
- Formula
- C27¹³C2H28D4ClN5O2·4H3PO4
- Molecular weight
- 916.04 g/mol
- Category
- Stable isotope labelled
Family: Pyronaridine
An antimalarial first synthesised in 1970 that entered clinical use in China in the 1980s: combined with artesunate, a derivative of artemisinin, it is used against malaria caused by Plasmodium falciparum and P. vivax.
Did you know?In 2017 its combination with artesunate was added to the WHO List of Essential Medicines; the molecule has also been studied as a possible anticancer drug and against the Ebola virus.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Pyronaridine family
Active ingredientPyronaridineCat. No. P-P241-001CAS 74847-35-1
MetabolitePyronaridine O-GlucuronideCat. No. P-P241-002
Isotopically labelledPyronaridine-13C2-d4Cat. No. P-P241-003CAS 1261393-31-0
NitrosamineN-Nitroso PyronaridineCat. No. P-P241-005
Impurity1-Aza-6,9-dichloro-2-methoxyacridineCat. No. P-P241-006CAS 6626-40-0
ImpurityPyronaridine Impurity 1Cat. No. P-P241-007CAS 81079-95-0
ImpurityPyronaridine Impurity 2Cat. No. P-P241-008CAS 81935-60-6
ImpurityPyronaridine Impurity 3Cat. No. P-P241-009CAS 1422180-92-4Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.