Active ingredientRabeprazoleCat. No. P-R001-001CAS 117976-89-3
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Stable isotope labelled · Rabeprazole family
Pharmaceutical analytical standardRabeprazole-d4
- Cat. No.
- P-R001-015
- CAS
- 934295-48-4
- Alternative CAS
- 117976-89-3 (unlabelled form)
- 117976-90-6 (unlabelled form, sodium salt)
- 891191-56-3 (unlabelled form, sodium salt hydrate)
- Formula
- C18H17D4N3O3S
- Molecular weight
- 363.47 g/mol
- Category
- Stable isotope labelled
Family: Rabeprazole
A proton pump inhibitor that reduces acid production in the stomach: patented in 1986, approved in Japan in 1997 and in the United States in 1999, it is used for ulcers, gastro-oesophageal reflux and eradication of Helicobacter pylori.
Did you know?Its main route of breakdown in the body needs no enzymes: it is chemically reduced to a thioether, while the liver enzymes CYP2C19 and CYP3A4 play only a secondary role.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Rabeprazole family
Active ingredientRabeprazoleCat. No. P-R001-001CAS 117976-89-3
Active ingredientRabeprazole SodiumCat. No. P-R001-002CAS 117976-90-6
Active ingredientRabeprazole sodium hydrateCat. No. P-R001-003CAS 891191-56-3
Pharmacopoeial impurityRabeprazole EP Impurity ACat. No. P-R001-005CAS 117976-47-3
Pharmacopoeial impurityRabeprazole EP Impurity BCat. No. P-R001-006CAS 117977-21-6
Pharmacopoeial impurityRabeprazole EP Impurity C Disodium SaltCat. No. P-R001-007
Pharmacopoeial impurityRabeprazole EP Impurity C Na SaltCat. No. P-R001-008CAS 2437254-50-5
Pharmacopoeial impurityRabeprazole EP Impurity DCat. No. P-R001-009CAS 924663-38-7Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.