Active ingredientSildenafilCat. No. P-S041-001CAS 139755-83-2
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Impurity or related compound · Sildenafil family
Pharmaceutical analytical standardSildenafil Impurity 61
- Cat. No.
- P-S041-144
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C37H44N10O8S2
- Molecular weight
- 820.94 g/mol
- Category
- Impurity or related compound
Family: Sildenafil
A phosphodiesterase-5 inhibitor born in the late 1980s as a possible medicine for angina. Approved in 1998 for erectile dysfunction, it is also used today for pulmonary arterial hypertension.
Did you know?In the angina trials the effect on the heart was disappointing, but volunteers reported an unexpected side effect: that is how the fate of the molecule changed.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Sildenafil family
Active ingredientSildenafilCat. No. P-S041-001CAS 139755-83-2
Active ingredientSildenafil CitrateCat. No. P-S041-002CAS 171599-83-0
Active ingredientSildenafil HydrochlorideCat. No. P-S041-003CAS 252920-86-8
Pharmacopoeial impuritySildenafil EP Impurity ACat. No. P-S041-004CAS 1391053-95-4
Pharmacopoeial impuritySildenafil EP Impurity BCat. No. P-S041-005CAS 1094598-75-0
Pharmacopoeial impuritySildenafil EP Impurity CCat. No. P-S041-006CAS 139755-91-2
Pharmacopoeial impuritySildenafil EP Impurity DCat. No. P-S041-007CAS 1357931-55-5
Pharmacopoeial impuritySildenafil EP Impurity D Sodium SaltCat. No. P-S041-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.