Active ingredientValproic AcidCat. No. P-V013-001CAS 99-66-1
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Active ingredient · Valproic Acid family
Pharmaceutical analytical standardSodium Valproate
Synonyms: sodium 2-propylpentanoate, Valproate sodium, Valproic acid sodium salt, Orfiril, Depacon, Selenica, NSC 732626, NSC 757376, Episenta, Kentilim, Orlept, Epilim iv, Epilim chronosphere, Epilim chrono 200, Epilim chrono 300, Epilim chrono 500, Monosodium 2-propylpentanoate, Valproic acid sodium, Pentanoic acid, 2-propyl-, sodium salt, Valerin, Valeric acid, 2-propyl-, sodium salt, Valproic acid sodium salt (Sodium valproate), Eurekene, Labazene, Depakene, Dipropylacetate sodium, Sodium dipropylacetate, Sodium valproate (2-Propylpentanoic acid, sodium salt), Sodium bispropylacetate, Sodium n-dipropylacetate, Valproate sodium salt, Sodium valproate (JP18), Sodium Valproate (Valproic acid sodium)
- Cat. No.
- P-V013-054
- CAS
- 1069-66-5
- Alternative CAS
- 99-66-1 (free acid)
- 33433-82-8 (calcium salt)
- 62959-43-7 (magnesium salt)
- 76584-70-8 (other salt)
- Formula
- C8H15NaO2
- Molecular weight
- 166.20 g/mol
- Category
- Active ingredient (API)
Family: Valproic Acid
A branched-chain fatty acid used as a broad-spectrum antiepileptic, as a mood stabiliser in bipolar disorder and to prevent migraine; it was first marketed in France in 1967.
Did you know?Synthesised in 1882, for decades it was merely a solvent: in the early 1960s in Grenoble, while it was being used to dissolve other molecules for testing, it was found by chance that it was the one stopping seizures.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Sodium ValproateBP 452
- Sodium valproate CRSEP S0930000
More products in the Valproic Acid family
Active ingredientValproic AcidCat. No. P-V013-001CAS 99-66-1
Pharmacopoeial impurityValproic Acid EP Impurity ACat. No. P-V013-002CAS 109-52-4
Pharmacopoeial impurityValproic Acid EP Impurity BCat. No. P-V013-003CAS 20225-24-5
Pharmacopoeial impurityValproic Acid EP Impurity CCat. No. P-V013-004CAS 62391-99-5
Pharmacopoeial impurityValproic Acid EP Impurity DCat. No. P-V013-005CAS 52061-75-3
Pharmacopoeial impurityValproic Acid EP Impurity ECat. No. P-V013-006CAS 626-97-1
Pharmacopoeial impurityValproic Acid EP Impurity FCat. No. P-V013-007CAS 2430-27-5
Pharmacopoeial impurityValproic Acid EP Impurity GCat. No. P-V013-008CAS 52061-73-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.