Isotopically labelledN-Hydroxyl Tetramethylpyrazine-d12Cat. No. P-T075-002
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Active ingredient · Tetramethylpyrazine family
Pharmaceutical analytical standardTetramethylpyrazine
Synonyms: 2,3,5,6-tetramethylpyrazine, Ligustrazine, Chuanxiongzine, Tetrapyrazine, Chuanxingzine, FEMA No. 3237, Chuanxiongqin, TMPZ, NSC 36080, NSC 46451, Pyrazine, tetramethyl-, Bs factor, Ligustizine, Liqustrazine, Pyrazine, 2,3,5,6-tetramethyl-, Ligustrazin
- Cat. No.
- P-T075-001
- CAS
- 1124-11-4
- Alternative CAS
- N/A
- Formula
- C8H12N2
- Molecular weight
- 136.20 g/mol
- Category
- Active ingredient (API)
An alkylpyrazine found in natto and fermented cocoa beans; under the name ligustrazine it is one of the main active ingredients of the rhizome of Ligusticum striatum (chuanxiong), a plant of traditional Chinese medicine, and it has been widely used in China for ischaemic cerebrovascular disease.
Did you know?In 1962 the researchers Kosuge, Adachi and Kamiya isolated it from cultures of Bacillus natto, the bacterium that ferments the soybeans of natto, and published the discovery in Nature.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Tetramethylpyrazine family
Isotopically labelledN-Hydroxyl Tetramethylpyrazine-d12Cat. No. P-T075-002
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ImpurityN-Hydroxyl TetramethylpyrazineCat. No. P-T075-004Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.