Tropicamide

Synonyms: N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide, Mydriacyl, Bistropamide, Tropicacyl, Mydriafair, Visumidriatic, Tropimil, N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide, N-Ethyl-N-(4-pyridylmethyl)tropamide, N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide, NSC 757372, Benzeneacetamide, N-ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)-, Opticyl, Mydral, OcuTropic, Mydriaticum, Epitromina, Mydrum, Tropikamid, N-ethyl-3-hydroxy-2-phenyl-N-(4-pyridylmethyl)propanamide, Triaminic DM, N-Ethyl-N-(4-pyridylmethyl)tropamid, Component of Paremyd, Hydracrylamide, N-ethyl-2-phenyl-N-(4-pyridylmethyl)-, Pharmakon1600-01500599, N-Ethyl-a-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide

Cat. No.: P-T228-001
CAS: 1508-75-4
Alternative CAS: 958623-78-4 (hydrochloride)
Formula: C₁₇H₂₀N₂O₂
Molecular weight: 284.36 g/mol
Category: Active ingredient (API)

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Characterisation level Level 1 Mass balanceFor small molecules, identity is confirmed by IR, MS, 1H-NMR and 13C-NMR, purity by HPLC (min. 95%) and assay by mass balance (min. 90%); for peptides and similar molecules, identity is confirmed by mass spectrometry (ESI-MS and MALDI-TOF) and IR, purity by HPLC (min. 95%) and assay by mass balance, reported for information only.* Level 2 Mass balance + qNMRFor small molecules, in addition to the Level 1 analyses, the assay is verified by qNMR, an orthogonal method independent of chromatography; for peptides and similar molecules, Level 2 is not available. Analytical documentation supporting qualification as an in-house primary standard under ICH Q7 (§11.17-11.18).

* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.

Quantity

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We reply within 24 hours with a quote and availability. CoA and SDS with every lot.

A short-acting antimuscarinic eye drop, approved in the United States in 1960: it dilates the pupil and temporarily blocks the eye's focusing, allowing the eye specialist to examine the back of the eye.

Did you know?It dilates the pupil like atropine from belladonna, Atropa bella-donna: Linnaeus chose that name with the plant's Renaissance cosmetic use in mind, when its drops are said to have been used to dilate the pupils.

The two levels compared

	Level 1 Mass balance	Level 2 Mass balance + qNMR
Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR)	✓	✓
HPLC purity (min. 95%)	✓	✓
Content by mass balance (min. 90%; peptides: for information only)*	✓	✓
Content verified by qNMR (small molecules only)	·	✓
Suitable to qualify it as an in-house primary standard (ICH Q7)	·	✓

What you receive

The analytical standard

Shipped under controlled temperature when the molecule requires it.

Certificate of analysis (CoA)

For every lot: identity, purity and assay, with the supporting spectra and chromatograms.

Safety data sheet (SDS)

Sent with every order.

Tracked shipment

Follow your shipment live, from our warehouse to your lab.

Pharmacopoeial standards available

The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.

TropicamideBP 1047
Tropicamide CRSEP T2580000
Tropicamide for peak identification CRSEP Y0001316

More products in the Tropicamide family

Pharmacopoeial impurityTropicamide EP Impurity CCat. No. P-T228-002CAS 529-64-6

Pharmacopoeial impurityTropicamide EP Impurity ACat. No. P-T228-003CAS 33403-97-3

Pharmacopoeial impurityTropicamide EP Impurity A DihydrochlorideCat. No. P-T228-004CAS 57786-23-9

Pharmacopoeial impurityTropicamide EP Impurity BCat. No. P-T228-005CAS 57322-50-6

ImpurityN-ethyl-3-hydroxy-2-phenylpropanamideCat. No. P-T228-006CAS 96392-48-2

See all 6 products in the family

Frequently asked questions

Is mass balance always performed?

Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.

Can I ask for a different quantity?

Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.

Which level should I choose?

Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.

When will I get the quote?

Within 24 working hours, with price, availability and delivery time.

Need a molecule you cannot find?

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