Active ingredientVigabatrinCat. No. P-V039-001CAS 68506-86-5
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Pharmacopoeial impurity · Vigabatrin family
Pharmaceutical analytical standardVigabatrin EP Impurity D
Synonyms: gamma-Aminobutyric Acid, 4-aminobutanoic acid, GABA, Piperidic acid, Piperidinic acid, Aminalon, Gaballon, Gamarex, Gammalon, Mielomade, Gammar, Gammasol, Butanoic acid, 4-amino-, Gammalone, Butyric acid, 4-amino-, gamma-Aminobutanoic acid, Immu-G, gamma-amino-n-butyric acid, Gammagee, Gamulin, omega-Aminobutyric acid, Aminalone, Factor I, Aminobutyric acid, gamma-, NSC 27418, Acid, Aminobutyric, Therafeldamine, Theraproxen, GABA Phenolic, Therapentin-60, Theraprofen-60, Theraprofen-90, Theraproxen-90, Theratramadol-60, Theratramadol-90, Theraprofen-800, Theraproxen-500, Theracodeine-300, Therabenzaprine-60, Therabenzaprine-90, Theracodophen-650, Theracodophen-750, Therabenzaprine-90-5, Carisoprodol, gaba, Gaba (Gamma-Aminobutyric Acid), Naproxen, gamma-aminobutyric acid, Ibuprofen, gamma-aminobutyric acid, Piroxicam, gamma-aminobutyric acid, Gabapentin, gamma-aminobutyric acid, HYDROCODONE, ACETAMINOPHEN, gamma-AMINOBUTYRIC ACID, Hydrocodone bitartrate, acetaminophen, gamma-aminobutyric acid, Aminobutyric Acid, Mielogen, Reanal, g-Aminobutyric acid, Aminobutanoic acid, EPA Pesticide Chemical Code 030802, gamma-Aminobutryic acid, Aminobutyrate, Immuglobin, Piperidate, Piperidinate, gamma-amino, Gamma aminobutyrate, omega-Aminobutyrate, a-Aminobutyric acid, w-Aminobutyric acid, Aminobutyric-4 acid, Aminobutyric acid,-4-, Pharmakon1600-01500678, DL-gamma-AMINO-n-BUTYRIC ACID, NSC 32044, NSC 45460, NSC 51295, NSC 757426, gamma-Aminobutyric acid (4-Aminobutyric acid), Vigabatrin impurity, gamma-aminobutyric acid-
- Cat. No.
- P-V039-009
- CAS
- 56-12-2
- Alternative CAS
- 651312-45-7 (hydrate)
- 5959-35-3 (hydrochloride)
- 70582-09-1 (calcium salt)
- 6610-05-5 (sodium salt)
- 2096495-60-0 (hydroiodide)
- 53504-43-1 (alternative CAS, same compound)
- 20-79-1 (alternative CAS, same compound)
- 60-28-6 (alternative CAS, same compound)
- Formula
- C4H9NO2
- Molecular weight
- 103.12 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Vigabatrin
An antiepileptic that irreversibly blocks GABA transaminase, the enzyme that breaks down GABA, so raising levels of this neurotransmitter in the brain. Approved in the United Kingdom in 1989 and in the United States in 2009, it is used for infantile spasms and epilepsies resistant to other medicines.
Did you know?It was purpose-built to switch the enzyme off for good: it is a copy of GABA with an extra vinyl group, hence the name gamma-vinyl-GABA, and of its two mirror-image forms only one is active.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Vigabatrin impurity D CRSEP Y0001404
More products in the Vigabatrin family
Active ingredientVigabatrinCat. No. P-V039-001CAS 68506-86-5
Active ingredientVigabatrin HClCat. No. P-V039-003CAS 1391054-02-6
Pharmacopoeial impurityVigabatrin EP Impurity BCat. No. P-V039-004CAS 1379403-11-8
Pharmacopoeial impurityVigabatrin EP Impurity ECat. No. P-V039-005CAS 1378466-25-1
Pharmacopoeial impurityVigabatrin EP Impurity ACat. No. P-V039-006CAS 7529-16-0
Pharmacopoeial impurityVigabatrin EP Impurity B HCl (Mixture of Z and E Isomers)Cat. No. P-V039-007
Pharmacopoeial impurityVigabatrin EP Impurity C (Mixture of Diastereomers)Cat. No. P-V039-008CAS 71107-19-2
Pharmacopoeial impurityVigabatrin EP Impurity F HCl (Mixture of Diastereomers)Cat. No. P-V039-010Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.