Active ingredientBerberine SulfateCat. No. P-B055-002CAS 316-41-6
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Active ingredient · Berberine family
Pharmaceutical analytical standardBerberine Chloride
Synonyms: Berberinum, Berberinium chloride, Benzodioxide, Natural Yellow 18 (chloride), Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, chloride, Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride, Umbellatine chloride, Berbinium,8,13,13a-tetradehydro-9.10-dimethoxy-2,3-(methylene dioxy)-, chloride
- Cat. No.
- P-B055-001
- CAS
- 633-65-8
- Alternative CAS
- 2086-83-1 (free base)
- 117-74-8 (hydrate)
- 633-66-9 (sulfate)
- 4263-84-7 (hydroiodide)
- 68005-98-1 (hydrate)
- 68030-18-2 (hydrate)
- 141433-60-5 (hydrate)
- 70399-14-3 (hydrate)
- 5956-60-5 (hydrate)
- 316-41-6 (sulfate)
- 6190-33-6 (sulfate)
- 69352-97-2 (sulfate hydrate)
- 2758467-95-5 (hydrobromide)
- Formula
- C20H18NO4·Cl
- Molecular weight
- 371.82 g/mol
- Category
- Active ingredient (API)
A yellow benzylisoquinoline alkaloid found in plants such as barberry (Berberis vulgaris), Coptis chinensis and goldenseal (Hydrastis canadensis), used in traditional medicine; in China it has been approved as an over-the-counter remedy for diarrhoea.
Did you know?Under ultraviolet light it gives off a strong yellow fluorescence, and its colour was put to use long ago: barberry was used to dye wool, leather and wood.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Berberine ChlorideBP 1108
- Berberine chloride CRSEP Y0001149
More products in the Berberine family
Active ingredientBerberine SulfateCat. No. P-B055-002CAS 316-41-6
Impurity13-Hydroxyberberine ChlorideCat. No. P-B055-003CAS 7664-25-7
Impurity13-Hydroxyberberine Inner SaltCat. No. P-B055-004CAS 62595-72-6
Impurity2,3,9,10-Tetrahydroxy Berberine ChlorideCat. No. P-B055-005CAS 248262-61-5
ImpurityBerberine Impurity 1Cat. No. P-B055-006CAS 1888416-22-5
Impurity7-(Benzyloxy)-8-hydroxyisochroman-3-oneCat. No. P-B055-007CAS 65615-22-7
Impurity7-(Benzyloxy)-8-methoxyisochroman-3-oneCat. No. P-B055-008CAS 65615-23-8
ImpurityBerberastine IodideCat. No. P-B055-009CAS 41759-65-3Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.