Active ingredientDextromethorphanCat. No. P-D079-001CAS 125-71-3
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Stable isotope labelled · Dextromethorphan family
Pharmaceutical analytical standardDextromethorphan-d3 HBr
- Cat. No.
- P-D079-012
- CAS
- 1279034-15-9
- Alternative CAS
- 125-69-9 (unlabelled form)
- 1887136-04-0 (unlabelled form)
- 125-71-3 (unlabelled form)
- 18609-21-7 (unlabelled form, hydrochloride)
- 6700-34-1 (unlabelled form, hydrate)
- 7487-74-3 (unlabelled form, hydroiodide)
- 1443149-12-9 (alternative CAS, same compound)
- Formula
- C18H22D3NO·HBr
- Molecular weight
- 355.33 g/mol
- Category
- Stable isotope labelled
Family: Dextromethorphan
A cough suppressant of the morphinan family, approved in the United States in 1958 for over-the-counter sale as an alternative to codeine; combined with quinidine it is also used for pseudobulbar affect.
Did you know?It is the mirror image of levomethorphan, the methyl ether of the opioid painkiller levorphanol: the prefix 'dextro' recalls that it rotates polarised light to the right.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Dextromethorphan family
Active ingredientDextromethorphanCat. No. P-D079-001CAS 125-71-3
Active ingredientDextromethorphan HBrCat. No. P-D079-002CAS 125-69-9
Active ingredientDextromethorphan Hydrobromide MonohydrateCat. No. P-D079-003CAS 6700-34-1
Pharmacopoeial impurityDextromethorphan EP Impurity A HClCat. No. P-D079-005CAS 1087-69-0
Pharmacopoeial impurityDextromethorphan EP Impurity CCat. No. P-D079-006CAS 57969-05-8
Pharmacopoeial impurityDextromethorphan EP Impurity DCat. No. P-D079-007CAS 1453167-99-1
Pharmacopoeial impurityDextromethorphan EP Impurity D Trinitrophenol SaltCat. No. P-D079-008
Isotopically labelledDextromethorphan-13C-d3 HBrCat. No. P-D079-011Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.